Document Details
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Document Type |
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Thesis |
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Document Title |
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Influence of Juniperus procera Leaves Extract on Male Rats Exposed to Lead تأثير مستخلص أوراق العرعر على ذكور الجرذان المعرضة للرصاص |
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Subject |
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Faculty of Science |
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Document Language |
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Arabic |
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Abstract |
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Globally, environmental pollution is a complex problem. Currently, the environment is increasingly exposed to chemical, biological and physical pollutants, and this pollution threatens ecosystem and sustainable development as a result of an increase in human activities. Environmental contamination by pollutants and toxicants is a worldwide problem. Exposures to environmental pollutants and toxicants are known causes of physiological and biochemical disorders, and complex health problems. Recently, interest has increased in using medicinal plants and natural products for pharmacological purposes, as a form of complementary or replacement therapy. Generally, herbal medicine is considered as an integral part of dietary supplement. The present study was aimed to evaluate the effect of juniper (Juniperus procera) leaves extract on male rats exposed to lead. Forty male rats were used in this study and divided into four groups. Rats of the first group were served as controls. Rats of the second group were exposed to lead. Rats of the third group were treated with juniper leaves extract and lead. Rats of the fourth group were treated with juniper leaves extract. Physiological alterations were investigated after six weeks. Rats exposed to lead and given the control diet had the lowest body weight gain. Significant alterations of blood alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, total bilirubin, total protein, albumin, glucose, triglycerides, cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, very low density lipoprotein cholesterol, creatinine, blood urea nitrogen, uric acid, creatine kinase, lactate dehydrogenase, glutathione and superoxide dismutase were observed in lead-treated rats. Administration of juniper leaves extract before lead exposure to rat can prevent severe alterations of physiological parameters. Finally, the present findings suggest that the protective effects of attributed to its antioxidant activity. |
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Supervisor |
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Dr. Sameera Abdullah Alghamdi |
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Thesis Type |
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Master Thesis |
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Publishing Year |
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1442 AH
2021 AD |
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Co-Supervisor |
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Prof. Dr. Atef Mohammed Al-Attar |
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Added Date |
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Friday, August 13, 2021 |
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Researchers
| شريفة عقيل العبدلي | Alabdali, Shareefa Aqeel | Researcher | Master | |
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